This 2.5mg estriol cream is the exact strength that is available by prescription from compounding pharmacies.
The benefits of estriol include:
It's the only estrogen that benefits vaginal dryness.
It's the only estrogen that does not cause cancer.
It can be utilized to help women withdraw from estradiol preparations.
It can help with hot flashes or night sweats.
Estriol can be beneficial to the skin and bones.
To get the most out of the cream, remove the bottom cap and push up the pump from underneath to unlodge any pressure.
Recommended dosages
For vaginal dryness: 
One pump placed intravaginally once a day for 10-14 days. 
Then one pump once or twice a month for maintenance.
For estrogen withdrawal or relief of hot flashes/night sweats: 
One pump applied to forearms every day as needed.